GOLGA4

Across TCGA patient cohorts, GOLGA4 mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA4-associated genes across cancer lineages are TSC1, cIAP, and Caspase-7-cleavedD198. Each is linked with GOLGA4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GOLGA4-to-partner and partner-to-GOLGA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSC1 grouped by GOLGA4-low versus GOLGA4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA4→partner) and Y-score (partner→GOLGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TSC1 →	-0.484	-3.313	<.001	.010	3	4
STAD	cIAP →	+0.160	+3.000	.032	.036	3	3
COAD	Caspase-7-cleavedD198 →	+1.552	+2.824	<.001	.034	3	3
UCEC	PCNA →	+0.249	+2.000	<.001	<.001	3	3
UCEC	ATM →	-0.554	-2.000	<.001	<.001	3	3
STAD	JNK2 →	+0.236	+3.000	.031	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

TSC1 by GOLGA4 expression — COAD

Explore this box plot interactively →