GOLGA4

Across TCGA cell cohorts, GOLGA4 mutation is significantly associated with the RNA expression of many other genes, with 550 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOLGA4-associated genes across cancer lineages are ASZ1, UBE2J2, and HHLA3. Each is linked with GOLGA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA4-to-partner and partner-to-GOLGA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASZ1 grouped by GOLGA4-low versus GOLGA4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA4→partner) and Y-score (partner→GOLGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ASZ1 →	+0.079	+3.304	.003	.001	3	2
LARGE_INTESTINE	UBE2J2 →	+0.547	+3.628	.001	<.001	3	2
LARGE_INTESTINE	HHLA3 →	+0.913	+2.588	.001	.004	3	2
URINARY_TRACT	NEUROG3 →	+0.005	+4.087	<.001	.009	3	1
URINARY_TRACT	SPATA31A6 →	+0.005	+4.087	<.001	.009	3	1
SOFT_TISSUE	CCR8 →	+0.016	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 550 associations by consensus.

ASZ1 by GOLGA4 expression — BLOOD_Leukemia

Explore this box plot interactively →