GOLGA3

Across TCGA pan-cancer cohorts, GOLGA3 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GOLGA3’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where GOLGA3 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types GOLGA3 is over-expressed in tumor.

CCRCC, LUAD, and LSCC are the cancer types where GOLGA3 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA3 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	Male	IV	+0.620	<.001	12	view →
LUAD	Female	II,III,IV	+0.492	<.001	9	view →
LSCC	Female	All	+0.235	<.001	7	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GOLGA3–CCRCC

Open the CCRCC breakdown →