GOLGA3

Across TCGA patient cohorts, GOLGA3 mutation is significantly associated with the total protein of many other genes, with 76 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GOLGA3-associated genes across cancer lineages are eEF2, c-Jun_pS73, and PDCD4. Each is linked with GOLGA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GOLGA3-to-partner and partner-to-GOLGA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by GOLGA3-low versus GOLGA3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA3→partner) and Y-score (partner→GOLGA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eEF2 →	+0.262	+3.169	.034	.018	3	4
LUSC	c-Jun_pS73 →	-0.203	-3.000	.017	.035	3	3
COAD	PDCD4 →	-0.482	-3.691	.006	.001	3	3
COAD	XRCC1 →	+0.232	+3.182	<.001	.009	2	4
COAD	Caspase-7-cleavedD198 →	+1.468	+3.338	<.001	.004	3	3
COAD	Chk1 →	+0.396	+3.169	<.001	.017	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

eEF2 by GOLGA3 expression — COAD

Explore this box plot interactively →