GOLGA3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA3 mutation is significantly associated with the RNA expression of many other genes, with 1,638 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOLGA3-associated genes across cancer lineages are OR2V2, LCE1F, and C19orf85. Each is linked with GOLGA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA3-to-partner and partner-to-GOLGA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2V2 grouped by GOLGA3-low versus GOLGA3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA3→partner) and Y-score (partner→GOLGA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASOR2V2 →+0.010+4.614<.001.00432
LUNG_SCLCLCE1F →+0.086+4.058<.001.00732
BLOOD_LymphomaC19orf85 →+0.057+3.754<.001.00232
OVARYOR2H1 →+0.015+2.859.002.00832
LARGE_INTESTINECLUAP1 →+0.600+2.438.001<.00132
LARGE_INTESTINEANKRD13C →+0.465+2.265.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,638 associations by consensus.

OR2V2 by GOLGA3 expression — PANCREAS

Box plot of OR2V2 in GOLGA3-low vs GOLGA3-high samples in PANCREAS.

Explore this box plot interactively →

Exploration