GOLGA2P5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA2P5 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA2P5-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and Annexin-1. Each is linked with GOLGA2P5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA2P5-to-partner and partner-to-GOLGA2P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by GOLGA2P5-low versus GOLGA2P5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA2P5→partner) and Y-score (partner→GOLGA2P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.345-3.000.017.03731
UCECeIF4E →+0.247+3.000.042.03731
UCECAnnexin-1 →+0.812+2.827.007.03531
UCEC14-3-3_beta →-0.145-2.986.012.03721
UCECTFRC →+0.771+3.000.012.03721
UCECC-Raf_pS338 →-0.115-3.000.015.03721
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

EGFR_pY1068 by GOLGA2P5 expression — UCEC

Box plot of EGFR_pY1068 in GOLGA2P5-low vs GOLGA2P5-high samples in UCEC.

Explore this box plot interactively →

Exploration