Across TCGA pan-cancer cohorts, GOLGA2P2Y RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of GOLGA2P2Y’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where GOLGA2P2Y RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA2P2Y is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.
BRCA and KIRC are the cancer types where GOLGA2P2Y tumor–normal differential expression is most reproducible.