GOLGA2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GOLGA2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GOLGA2 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GOLGA2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GOLGA2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and LUAD are the cancer types where GOLGA2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileII,III,IV1.0000.417.00234view →
HNSCDFSMedianAll0.8510.353.0288view →
LUADOSMedianIII,IV0.7820.449.0287view →
PDACOSMedianIV0.4910.836.0243view →
CCRCCDFSMedianAll1.0000.733.0202view →
GBMOSQuartileAll0.6190.864.0391view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GOLGA2–UCEC (DFS)

Kaplan–Meier survival curve for GOLGA2 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration