GOLGA2

Across TCGA patient cohorts, GOLGA2 mutation is significantly associated with the RNA expression of many other genes, with 2,867 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA2-associated genes across cancer lineages are MIER3, PGGT1B, and CHAF1A. Each is linked with GOLGA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GOLGA2-to-partner and partner-to-GOLGA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIER3 grouped by GOLGA2-low versus GOLGA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA2→partner) and Y-score (partner→GOLGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIER3 →	+0.453	+1.847	.002	<.001	3	3
UCEC	PGGT1B →	+0.346	+3.828	.004	<.001	3	3
UCEC	CHAF1A →	+0.583	+2.454	<.001	<.001	3	3
UCEC	REEP4 →	+0.458	+2.126	<.001	<.001	3	3
BLCA	RIMKLA →	+0.656	+3.212	.007	.009	3	3
UCEC	FAM136A →	+0.313	+2.313	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,867 associations by consensus.

MIER3 by GOLGA2 expression — UCEC

Explore this box plot interactively →