GOLGA2

Across TCGA patient cohorts, GOLGA2 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA2-associated genes across cancer lineages are ERK2, MEK1, and MSH2. Each is linked with GOLGA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA2-to-partner and partner-to-GOLGA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by GOLGA2-low versus GOLGA2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA2→partner) and Y-score (partner→GOLGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ERK2 →	+0.206	+2.195	.023	.034	3	2
UCEC	MEK1 →	+0.403	+2.070	.001	.001	3	2
UCEC	MSH2 →	-0.261	-1.674	.001	.040	3	2
UCEC	P-Cadherin →	-0.158	-2.906	.001	.001	3	2
UCEC	STAT3_pY705 →	-0.379	-3.906	<.001	<.001	3	2
UCEC	Cyclin-B1 →	+0.512	+2.584	.008	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

ERK2 by GOLGA2 expression — COAD

Explore this box plot interactively →