GOLGA2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA2 mutation is significantly associated with the RNA expression of many other genes, with 696 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA2-associated genes across cancer lineages are ACVR2B, ATF2, and S100PBP. Each is linked with GOLGA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA2-to-partner and partner-to-GOLGA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACVR2B grouped by GOLGA2-low versus GOLGA2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA2→partner) and Y-score (partner→GOLGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaACVR2B →+0.796+3.199.004.00732
BLOOD_LeukemiaATF2 →+0.573+3.199.004.00732
BLOOD_LeukemiaS100PBP →+0.722+3.199.001.00732
BLOOD_LeukemiaCDAN1 →+0.591+3.199.002.00732
BLOOD_LeukemiaCNOT9 →+0.474+3.199.005.00732
BLOOD_LeukemiaPRSS53 →+0.655+3.215<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 696 associations by consensus.

ACVR2B by GOLGA2 expression — BLOOD_Leukemia

Box plot of ACVR2B in GOLGA2-low vs GOLGA2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration