GOLGA1

Across TCGA patient cohorts, GOLGA1 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA1-associated genes across cancer lineages are STAT3_pY705, Cyclin-B1, and EGFR_pY1173. Each is linked with GOLGA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GOLGA1-to-partner and partner-to-GOLGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by GOLGA1-low versus GOLGA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA1→partner) and Y-score (partner→GOLGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.299	-1.415	<.001	.040	3	3
UCEC	Cyclin-B1 →	+0.414	+1.247	.030	.045	3	3
UCEC	EGFR_pY1173 →	+0.062	+1.274	.022	.028	3	2
UCEC	4E-BP1 →	+0.213	+1.730	.021	.025	3	2
UCEC	C-Raf →	+0.107	+1.678	.029	.021	3	2
UCEC	IGFBP2 →	-0.687	-2.584	.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

STAT3_pY705 by GOLGA1 expression — UCEC

Explore this box plot interactively →