Q-omics provides the consensus-scored GNRHR2P1 profile across patient tissues and cancer cell-line models. GNRHR2P1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, GNRHR2P1 is differentially expressed in 3, with the highest sampling consensus in BLCA. Additionally, GNRHR2P1 RNA expression shows 5,725 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCEC, BLCA, and STAD as cancer lineages where GNRHR2P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GNRHR2P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GNRHR2P1 survival associations across molecular data types. GNRHR2P1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GNRHR2P1 RNA expression–survival associations across cancer types. High GNRHR2P1 expression shows unfavorable associations in UCEC, LUSC, THCA and LUAD, but favorable associations in KIRC and CESC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify UCEC as the clearest survival context for GNRHR2P1 RNA expression.
This table summarizes GNRHR2P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in PAAD for RNA.
This table ranks reproducible tumor–normal expression differences for GNRHR2P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GNRHR2P1 shows lower tumor expression in PAAD and STAD and higher tumor expression in BLCA. The BLCA box plot shows higher GNRHR2P1 RNA expression in tumor versus normal tissue (log2 FC = +0.170, t-test p = .002).
This table shows molecular features associated with GNRHR2P1 in patient tissues and cancer cell lines. In patient samples, GNRHR2P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
