GNPTG

Across TCGA patient cohorts, GNPTG protein abundance is significantly associated with the RNA expression of many other genes, with 7,961 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GNPTG-associated genes across cancer lineages are SIT1, MAL, and ETV7. Each is linked with GNPTG in more than 3 cancer types. Because this analysis shows association rather than direction, both GNPTG-to-partner and partner-to-GNPTG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNPTG versus SIT1 in OV, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPTG→partner) and Y-score (partner→GNPTG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SIT1 →	-0.974	-0.305	.002	<.001	3	4
HNSC	MAL →	-1.260	-0.099	.007	.009	3	4
OV	ETV7 →	-1.034	-0.310	<.001	.003	3	3
OV	SET →	-0.555	-0.368	<.001	<.001	3	3
OV	NDUFA8 →	-0.749	-0.337	<.001	<.001	3	3
BRCA	AIF1L →	-1.282	-0.250	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,961 associations by consensus.

GNPTG vs SIT1 — OV

Explore this scatter interactively →