GNPTG

Across TCGA cell cohorts, GNPTG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,796 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GNPTG-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Cilium movement involved in cell motility, and Lysosome organization. Each is linked with GNPTG in more than 15 cancer types. Because this analysis shows association rather than direction, both GNPTG-to-partner and partner-to-GNPTG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by GNPTG-low versus GNPTG-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPTG→partner) and Y-score (partner→GNPTG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Calcium-independent cell-matrix adhesion →	+0.258	+0.734	<.001	.001	3	16
BONE	Cilium movement involved in cell motility →	-0.114	-0.893	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Lysosome organization →	+0.087	+1.286	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Lytic vacuole organization →	+0.087	+1.286	<.001	<.001	3	15
SKIN	Methylglyoxal metabolic process →	+0.127	+1.098	<.001	<.001	3	15
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.171	+0.613	.005	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,796 associations by consensus.

Calcium-independent cell-matrix adhesion by GNPTG expression — URINARY_TRACT

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