GNPDA2

Across TCGA patient cohorts, GNPDA2 mutation is significantly associated with the RNA expression of many other genes, with 3,143 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GNPDA2-associated genes across cancer lineages are NCMAP-DT, ELOCP27, and VCY. Each is linked with GNPDA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNPDA2-to-partner and partner-to-GNPDA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCMAP-DT grouped by GNPDA2-low versus GNPDA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPDA2→partner) and Y-score (partner→GNPDA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCMAP-DT →	+0.244	+2.815	<.001	.002	3	2
UCEC	ELOCP27 →	+0.339	+2.085	.001	<.001	3	2
LUAD	VCY →	+0.179	+7.924	<.001	<.001	3	2
LUSC	RBMY2QP →	+0.507	+5.474	<.001	.005	3	2
UCEC	RPS10-NUDT3 →	+0.201	+1.839	.002	.006	3	1
UCEC	LINC02427 →	-0.234	-2.831	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,143 associations by consensus.

NCMAP-DT by GNPDA2 expression — UCEC

Explore this box plot interactively →