GNPDA1

Across TCGA pan-cancer cohorts, GNPDA1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GNPDA1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GNPDA1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GNPDA1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where GNPDA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.879	1.000	.018	42	view →
CCRCC	DFS	Median	II,III,IV	0.887	0.283	.012	29	view →
PDAC	DFS	Quartile	All	0.619	0.335	.013	23	view →
LUAD	DFS	Quartile	All	0.765	0.358	.006	11	view →
HNSC	DFS	Median	III,IV	0.874	0.691	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GNPDA1–COAD (DFS)

Open the COAD breakdown →