GNPAT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GNPAT RNA expression is significantly associated with the protein abundance of many other proteins, with 14,872 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNPAT-associated proteins across cancer lineages are PARP1, C1orf35, and BROX. Each is linked with GNPAT in more than 8 cancer types. Because this analysis shows association rather than direction, both GNPAT-to-partner and partner-to-GNPAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNPAT versus PARP1 in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPAT→partner) and Y-score (partner→GNPAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPARP1 →+0.441+0.653<.001<.00139
BRCAC1orf35 →+0.523+0.478<.001<.00138
OVBROX →+0.699+0.520<.001<.00138
BRCAPRCC →+0.280+0.408<.001<.00137
HNSCARID4B →+0.342+1.006<.001<.00137
OVBPNT1 →+0.575+0.556<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,872 associations by consensus.

GNPAT vs PARP1 — HNSC

Per-sample scatter of GNPAT vs PARP1 in HNSC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration