GNPAT

Across TCGA cell cohorts, GNPAT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,876 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GNPAT-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum membrane, Nuclear pore organization, and Regulation of endoplasmic reticulum tubular network organization. Each is linked with GNPAT in more than 13 cancer types. Because this analysis shows association rather than direction, both GNPAT-to-partner and partner-to-GNPAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum membrane grouped by GNPAT-low versus GNPAT-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNPAT→partner) and Y-score (partner→GNPAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Establishment of protein localization to endoplasmic reticulum membrane →	+0.115	+0.624	<.001	<.001	3	14
BONE	Nuclear pore organization →	+0.197	+1.032	<.001	<.001	3	13
KIDNEY	Regulation of endoplasmic reticulum tubular network organization →	+0.125	+0.707	.002	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.136	+0.771	.003	.001	3	11
SOFT_TISSUE	Positive regulation of mRNA processing →	+0.121	+0.766	<.001	<.001	3	11
SOFT_TISSUE	RNA export from nucleus →	+0.083	+0.547	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,876 associations by consensus.

Establishment of protein localization to endoplasmic reticulum membrane by GNPAT expression — SKIN

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