GNL3

Across TCGA patient cohorts, GNL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,688 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNL3-associated proteins across cancer lineages are SMARCC1, DCP1A, and SNRPD2. Each is linked with GNL3 in more than 7 cancer types. Because this analysis shows association rather than direction, both GNL3-to-partner and partner-to-GNL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNL3 versus SMARCC1 in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNL3→partner) and Y-score (partner→GNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMARCC1 →	+0.514	+0.569	<.001	<.001	3	8
OV	DCP1A →	+0.274	+0.593	<.001	<.001	3	8
GBM	SNRPD2 →	+0.320	+0.453	<.001	<.001	3	7
COAD	MCM2_S41 →	+0.519	+0.410	.001	.002	3	7
UCEC	RPP40 →	+0.243	+0.773	.001	.001	3	6
OV	RRP9 →	+0.407	+0.610	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,688 associations by consensus.

GNL3 vs SMARCC1 — LSCC

Explore this scatter interactively →