GNL2

Across TCGA patient cohorts, GNL2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,392 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNL2-associated genes across cancer lineages are KIF2C, LMOD1, and CDCA8. Each is linked with GNL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GNL2-to-partner and partner-to-GNL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNL2 versus KIF2C in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNL2→partner) and Y-score (partner→GNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF2C →	+1.288	+0.360	<.001	<.001	3	9
CCRCC	LMOD1 →	-1.511	-0.333	<.001	<.001	3	9
BRCA	CDCA8 →	+1.122	+0.436	<.001	<.001	3	9
LUAD	RRM2 →	+0.983	+0.279	<.001	<.001	3	9
LSCC	CENPI →	+1.016	+0.383	<.001	<.001	3	8
BRCA	CDC20 →	+1.493	+0.458	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,392 associations by consensus.

GNL2 vs KIF2C — BRCA

Explore this scatter interactively →