GNL2

Across TCGA cell cohorts, GNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,185 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GNL2-associated GO terms across cancer lineages are rRNA processing, Maturation of SSU-rRNA, and Ribosome biogenesis. Each is linked with GNL2 in more than 16 cancer types. Because this analysis shows association rather than direction, both GNL2-to-partner and partner-to-GNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA processing grouped by GNL2-low versus GNL2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNL2→partner) and Y-score (partner→GNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	rRNA processing →	+0.105	+0.458	.001	.008	2	17
OESOPHAGUS	Maturation of SSU-rRNA →	+0.137	+0.609	.001	.002	3	16
BONE	Ribosome biogenesis →	+0.116	+0.758	.008	.003	3	16
BONE	rRNA metabolic process →	+0.103	+0.707	.003	<.001	3	16
PANCREAS	snRNA pseudouridine synthesis →	+0.077	+0.629	.005	<.001	3	15
BLOOD_Myeloma	Nuclear pore localization →	+0.184	+0.641	.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,185 associations by consensus.

rRNA processing by GNL2 expression — OESOPHAGUS

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