Across TCGA patient cohorts, GNL1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,161 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNL1-associated genes across cancer lineages are ZSCAN26, RXRB, and RNF5. Each is linked with GNL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GNL1-to-partner and partner-to-GNL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNL1→partner) and Y-score (partner→GNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZSCAN26 →	+0.677	+0.219	.004	<.001	3	8
LSCC	RXRB →	+0.514	+0.305	<.001	<.001	3	8
OV	RNF5 →	+0.631	+0.308	<.001	<.001	3	8
HNSC	PRR3 →	+0.814	+0.230	<.001	<.001	3	8
LUAD	PPP1R11 →	+0.460	+0.215	<.001	<.001	3	8
UCEC	ZSCAN12 →	+0.865	+0.204	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,161 associations by consensus.

Exploration

GNL1 survival (RNA) · tumor vs normal (RNA) · all GNL1 data types