Across TCGA patient cohorts, GNL1 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,631 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNL1-associated proteins across cancer lineages are RXRB, ABCF1, and DEK. Each is linked with GNL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GNL1-to-partner and partner-to-GNL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNL1→partner) and Y-score (partner→GNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RXRB →	+0.319	+0.211	<.001	<.001	3	7
LSCC	ABCF1 →	+0.305	+0.341	<.001	<.001	3	7
OV	DEK →	+0.356	+0.244	<.001	<.001	3	7
LSCC	XPO1 →	+0.232	+0.309	<.001	<.001	3	6
LSCC	XPO5 →	+0.562	+0.297	<.001	<.001	3	6
OV	NUP153 →	+0.347	+0.415	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,631 associations by consensus.

Exploration

GNL1 survival (RNA) · tumor vs normal (RNA) · all GNL1 data types