GNG5P3

Across TCGA pan-cancer cohorts, GNG5P3 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GNG5P3 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher GNG5P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GNG5P3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and COAD show a favorable association.

READ, DLBC, and LUSC are the cancer types where GNG5P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.526	0.854	<.001	81	view →
DLBC	OS	Tertile	IV	0.147	0.850	.002	42	view →
LUSC	OS	Tertile	III,IV	0.322	0.693	.002	36	view →
THYM	DFS	Tertile	III,IV	0.212	0.862	.005	33	view →
KIRP	DFS	Tertile	All	0.829	0.924	.004	27	view →
SKCM	DFS	Tertile	III,IV	0.347	0.534	.011	21	view →
BRCA	OS	Tertile	III,IV	0.856	0.916	.031	18	view →
MESO	OS	Tertile	IV	0.203	0.661	.003	18	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
UCS	OS	Tertile	All	0.315	0.628	.043	18	view →
ESCA	OS	Median	III,IV	0.523	0.317	.022	12	view →
TGCT	DFS	Tertile	All	0.603	0.817	.027	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

GNG5P3–READ (DFS)

Open the READ breakdown →