GNG5P2

Across TCGA pan-cancer cohorts, GNG5P2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GNG5P2 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GNG5P2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GNG5P2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

LUAD, HNSC, and LSCC are the cancer types where GNG5P2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.651	1.000	.013	20	view →
HNSC	DFS	Median	III,IV	1.000	0.883	.021	6	view →
LSCC	DFS	Tertile	All	1.000	0.609	.049	2	view →
GBM	OS	Tertile	All	0.320	0.666	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GNG5P2–LUAD (OS)

Open the LUAD breakdown →