GNG4

Across TCGA patient cohorts, GNG4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,659 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNG4-associated genes across cancer lineages are TERF1, DOK1, and VAMP8. Each is linked with GNG4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GNG4-to-partner and partner-to-GNG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG4 versus TERF1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG4→partner) and Y-score (partner→GNG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TERF1 →	+0.440	+0.402	.002	.005	3	3
COAD	DOK1 →	-0.638	-1.013	.001	.002	3	3
GBM	VAMP8 →	-0.762	-0.492	<.001	<.001	3	3
LUAD	HLA-DQA1 →	-1.250	-0.614	<.001	.004	3	3
LUAD	PBK →	+1.824	+0.857	<.001	.007	2	4
HNSC	POLR3D →	+0.597	+0.358	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,659 associations by consensus.

GNG4 vs TERF1 — HNSC

Explore this scatter interactively →