Across TCGA patient cohorts, GNG2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,152 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNG2-associated genes across cancer lineages are ANKRD44, PPP1R16B, and CLEC1A. Each is linked with GNG2 in more than 9 cancer types. Because this analysis shows association rather than direction, both GNG2-to-partner and partner-to-GNG2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG2→partner) and Y-score (partner→GNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+1.020	+0.692	<.001	<.001	3	10
GBM	PPP1R16B →	+1.680	+0.731	<.001	<.001	3	9
OV	CLEC1A →	+0.724	+0.605	<.001	.001	3	9
BRCA	FLI1 →	+0.811	+0.574	<.001	<.001	3	9
OV	ARHGAP25 →	+0.909	+0.780	<.001	<.001	3	9
GBM	PRKCB →	+1.043	+0.609	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,152 associations by consensus.

Exploration

GNG2 survival (RNA) · tumor vs normal (RNA) · all GNG2 data types