Across TCGA patient cohorts, GNG2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GNG2-associated genes across cancer lineages are Macrophages M2 and Epithelial cells. Each is linked with GNG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNG2-to-partner and partner-to-GNG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG2→partner) and Y-score (partner→GNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Macrophages M2 →	+0.018	+3.118	.002	.016	2	1
UCEC	Epithelial cells →	-0.110	-3.000	.008	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

GNG2 survival (RNA) · tumor vs normal (RNA) · all GNG2 data types