GNG2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GNG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,016 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GNG2-associated GO terms across cancer lineages are Positive regulation of extracellular matrix organization, Dentate gyrus development, and IRE1-mediated unfolded protein response. Each is linked with GNG2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GNG2-to-partner and partner-to-GNG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG2→partner) and Y-score (partner→GNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERPositive regulation of extracellular matrix organization →+0.167+2.403<.001<.00139
BLOOD_LeukemiaDentate gyrus development →+0.122+1.899<.001<.00139
SOFT_TISSUEIRE1-mediated unfolded protein response →+0.121+1.586<.001<.00139
LIVERRegulation of plasminogen activation →+0.283+1.834<.001<.00139
LIVERRegulation of protein localization to mitochondrion →+0.116+2.418<.001<.00139
LUNG_NSCLC_LUADPML body organization →+0.184+1.153<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,016 associations by consensus.

Exploration