GNG14

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GNG14 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,536 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNG14-associated proteins across cancer lineages are WIZ, PPP1R18_S368, and RNPS1. Each is linked with GNG14 in more than 2 cancer types. Because this analysis shows association rather than direction, both GNG14-to-partner and partner-to-GNG14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG14 versus WIZ in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG14→partner) and Y-score (partner→GNG14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWIZ →+0.303+0.282<.001.00333
COADPPP1R18_S368 →-0.557-0.172.003.00733
LSCCRNPS1 →+0.192+0.254<.001.00133
HNSCUPF1 →+0.152+0.232.002.00133
LSCCPRR36 →+0.868+0.273.001.00133
LSCCSMC5 →+0.209+0.252.002<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,536 associations by consensus.

GNG14 vs WIZ — GBM

Per-sample scatter of GNG14 vs WIZ in GBM (Pearson r = 0.30).

Explore this scatter interactively →

Exploration