GNG14

Across TCGA patient cohorts, GNG14 protein abundance is significantly associated with the RNA expression of many other genes, with 382 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNG14-associated genes across cancer lineages are MAPK1, TTC28, and PCYT1B. Each is linked with GNG14 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNG14-to-partner and partner-to-GNG14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG14 versus MAPK1 in LSCC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG14→partner) and Y-score (partner→GNG14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAPK1 →	-0.387	-1.296	.008	.001	3	1
LSCC	TTC28 →	-0.837	-1.665	<.001	<.001	3	1
LSCC	PCYT1B →	-1.265	-1.470	.009	.009	3	1
LSCC	MEFV →	+1.079	+1.480	.001	.002	3	1
LSCC	TMEM106B →	-0.670	-1.395	.009	<.001	3	1
LSCC	SPIN1 →	-0.559	-1.560	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 382 associations by consensus.

GNG14 vs MAPK1 — LSCC

Explore this scatter interactively →