GNG12

Across TCGA patient cohorts, GNG12 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,427 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GNG12-associated proteins across cancer lineages are GNG12_S49, SNX7, and SSH3. Each is linked with GNG12 in more than 5 cancer types. Because this analysis shows association rather than direction, both GNG12-to-partner and partner-to-GNG12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG12 versus GNG12_S49 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG12→partner) and Y-score (partner→GNG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GNG12_S49 →	+0.937	+0.404	<.001	<.001	3	6
LSCC	SNX7 →	+0.427	+0.692	<.001	<.001	3	6
BRCA	SSH3 →	+0.495	+0.855	<.001	.001	3	5
PDAC	FHL2 →	+0.659	+0.399	<.001	<.001	3	5
PDAC	TAX1BP3 →	+0.436	+0.304	.003	.006	3	5
LSCC	TOP1 →	-0.359	-0.453	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,427 associations by consensus.

GNG12 vs GNG12_S49 — PDAC

Explore this scatter interactively →