GNG10

Across TCGA pan-cancer cohorts, GNG10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GNG10 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GNG10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GNG10 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

COAD, LUAD, and PDAC are the cancer types where GNG10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.914	1.000	.017	66	view →
LUAD	OS	Tertile	All	0.739	0.960	<.001	41	view →
PDAC	DFS	Quartile	All	0.225	0.583	.003	26	view →
LSCC	OS	Tertile	All	0.931	0.698	.010	5	view →
CCRCC	DFS	Median	II,III,IV	0.804	0.958	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GNG10–COAD (DFS)

Open the COAD breakdown →