GNG10

Across TCGA patient cohorts, GNG10 protein abundance is significantly associated with the RNA expression of many other genes, with 5,862 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GNG10-associated genes across cancer lineages are SIGLEC10, FCER1G, and FCGR1B. Each is linked with GNG10 in more than 4 cancer types. Because this analysis shows association rather than direction, both GNG10-to-partner and partner-to-GNG10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG10 versus SIGLEC10 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG10→partner) and Y-score (partner→GNG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIGLEC10 →	+1.136	+0.621	<.001	<.001	3	5
COAD	FCER1G →	+1.016	+0.485	<.001	.001	3	5
GBM	FCGR1B →	+0.648	+0.732	.001	.001	3	5
PDAC	GPR68 →	+0.835	+0.420	<.001	.001	3	4
LUAD	SIGLEC9 →	+0.696	+0.444	<.001	<.001	3	4
COAD	APOE →	+1.618	+0.396	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,862 associations by consensus.

GNG10 vs SIGLEC10 — GBM

Explore this scatter interactively →