GNG10

Across TCGA patient cohorts, GNG10 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,502 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GNG10-associated proteins across cancer lineages are CYBA, CYBB, and TRPV2. Each is linked with GNG10 in more than 6 cancer types. Because this analysis shows association rather than direction, both GNG10-to-partner and partner-to-GNG10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNG10 versus CYBA in OV, with a Pearson correlation of 0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG10→partner) and Y-score (partner→GNG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CYBA →	+0.775	+0.875	<.001	<.001	3	6
PDAC	CYBB →	+1.103	+0.813	<.001	<.001	3	6
BRCA	TRPV2 →	+0.510	+0.490	<.001	.001	3	6
GBM	GNG5 →	+0.426	+0.651	<.001	<.001	3	6
BRCA	ARHGEF6_S225 →	+0.675	+0.490	.001	.002	2	6
PDAC	GNAI2 →	+0.444	+0.734	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,502 associations by consensus.

GNG10 vs CYBA — OV

Explore this scatter interactively →