GNG10

Across TCGA cell cohorts, GNG10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,977 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GNG10-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Body fluid secretion, and Positive regulation of chromosome condensation. Each is linked with GNG10 in more than 12 cancer types. Because this analysis shows association rather than direction, both GNG10-to-partner and partner-to-GNG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by GNG10-low versus GNG10-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNG10→partner) and Y-score (partner→GNG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Immunoglobulin heavy chain V-D-J recombination →	+0.165	+0.936	.002	.004	3	13
STOMACH	Body fluid secretion →	-0.257	-1.695	<.001	.004	3	12
LUNG_NSCLC_LUSC	Positive regulation of chromosome condensation →	+0.217	+0.968	.001	.004	3	11
LUNG_NSCLC_LUSC	Proteasome regulatory particle assembly →	+0.156	+1.008	<.001	.001	3	11
SKIN	Regulation of tRNA catabolic process →	-0.109	-0.765	.001	<.001	3	10
SKIN	Negative regulation of tRNA catabolic process →	-0.109	-0.765	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,977 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by GNG10 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →