GNB5

Across TCGA patient cohorts, GNB5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,745 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNB5-associated proteins across cancer lineages are HDGFL3, MRPS5, and WDR13. Each is linked with GNB5 in more than 6 cancer types. Because this analysis shows association rather than direction, both GNB5-to-partner and partner-to-GNB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNB5 versus HDGFL3 in BRCA, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB5→partner) and Y-score (partner→GNB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.648	+0.511	.001	.001	3	7
OV	MRPS5 →	-0.400	-0.609	<.001	.002	3	6
OV	WDR13 →	+0.258	+0.596	.003	<.001	3	5
BRCA	UBR1 →	+0.198	+0.383	.002	.003	3	5
LUAD	MRPS6 →	-0.404	-0.318	<.001	.002	3	5
OV	GDI1 →	+0.269	+0.515	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,745 associations by consensus.

GNB5 vs HDGFL3 — BRCA

Explore this scatter interactively →