GNB5

Across TCGA cell cohorts, GNB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,128 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GNB5-associated GO terms across cancer lineages are Microtubule polymerization, Mitotic cytokinesis, and Regulation of hippo signaling. Each is linked with GNB5 in more than 15 cancer types. Because this analysis shows association rather than direction, both GNB5-to-partner and partner-to-GNB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by GNB5-low versus GNB5-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB5→partner) and Y-score (partner→GNB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule polymerization →	+0.093	+1.233	<.001	<.001	3	16
SKIN	Mitotic cytokinesis →	+0.075	+1.089	<.001	<.001	3	15
STOMACH	Regulation of hippo signaling →	+0.105	+1.132	<.001	.001	3	15
BREAST	Cell division →	+0.069	+1.231	.003	<.001	3	15
LARGE_INTESTINE	Positive regulation of mitotic cytokinesis →	+0.137	+1.624	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.072	+0.823	.003	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,128 associations by consensus.

Microtubule polymerization by GNB5 expression — LARGE_INTESTINE

Explore this box plot interactively →