GNB4

Across TCGA cell cohorts, GNB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,888 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible GNB4-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Positive regulation of mitotic cell cycle, and Mitotic sister chromatid segregation. Each is linked with GNB4 in more than 13 cancer types. Because this analysis shows association rather than direction, both GNB4-to-partner and partner-to-GNB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by GNB4-low versus GNB4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB4→partner) and Y-score (partner→GNB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Microtubule cytoskeleton organization involved in mitosis →	+0.077	+1.964	<.001	.001	3	13
KIDNEY	Positive regulation of mitotic cell cycle →	+0.078	+2.133	.003	.001	3	13
STOMACH	Mitotic sister chromatid segregation →	+0.082	+2.266	.006	.008	2	14
STOMACH	Positive regulation of mitotic cell cycle phase transition →	+0.088	+2.050	.001	.004	3	12
URINARY_TRACT	Regulation of chromosome segregation →	+0.106	+2.630	<.001	<.001	3	12
OESOPHAGUS	Chromosome segregation →	+0.080	+1.364	.005	.004	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,888 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by GNB4 expression — BLOOD_Lymphoma

Explore this box plot interactively →