GNB2

Across TCGA patient cohorts, GNB2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,328 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GNB2-associated genes across cancer lineages are TRIM4, MYL3, and TNXB. Each is linked with GNB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GNB2-to-partner and partner-to-GNB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNB2 versus TRIM4 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB2→partner) and Y-score (partner→GNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRIM4 →	+0.644	+0.217	<.001	.002	3	5
HNSC	MYL3 →	+0.885	+0.367	.005	<.001	3	5
UCEC	TNXB →	+1.185	+0.265	<.001	.004	3	5
GBM	ADGRG3 →	-0.961	-0.359	<.001	<.001	3	5
UCEC	KLHDC1 →	+0.841	+0.400	<.001	<.001	3	5
GBM	GGTA1 →	+0.812	+0.315	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,328 associations by consensus.

GNB2 vs TRIM4 — OV

Explore this scatter interactively →