Across TCGA patient cohorts, GNB1L protein abundance is significantly associated with the RNA expression of many other genes, with 6,360 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GNB1L-associated genes across cancer lineages are SRSF5, CLEC2B, and SUCLG2. Each is linked with GNB1L in more than 2 cancer types. Because this analysis shows association rather than direction, both GNB1L-to-partner and partner-to-GNB1L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB1L→partner) and Y-score (partner→GNB1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SRSF5 →	-0.435	-0.221	<.001	<.001	3	3
GBM	CLEC2B →	-0.773	-0.186	.005	.006	3	3
BRCA	SUCLG2 →	-0.815	-0.328	<.001	<.001	3	3
BRCA	COL14A1 →	-0.990	-0.229	.001	<.001	3	3
CCRCC	AQP1 →	-1.129	-0.182	.001	.001	3	3
GBM	MRC1 →	-1.210	-0.185	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,360 associations by consensus.

Exploration

GNB1L survival (RNA) · tumor vs normal (RNA) · all GNB1L data types