Across TCGA cell cohorts, GNB1L mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GNB1L-associated genes across cancer lineages are TLX3, LRRC72, and CNTNAP3C. Each is linked with GNB1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GNB1L-to-partner and partner-to-GNB1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB1L→partner) and Y-score (partner→GNB1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TLX3 →	+1.796	+3.944	<.001	.006	3	1
BLOOD_Leukemia	LRRC72 →	+0.019	+3.874	<.001	.005	3	1
BLOOD_Leukemia	CNTNAP3C →	+0.089	+3.729	.003	.009	3	1
BLOOD_Leukemia	FNDC1 →	+0.034	+3.712	.008	.009	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

GNB1L survival (RNA) · tumor vs normal (RNA) · all GNB1L data types