GNB1

Across TCGA patient cohorts, GNB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,736 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GNB1-associated proteins across cancer lineages are PGD, ICMT, and PANK4. Each is linked with GNB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GNB1-to-partner and partner-to-GNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNB1 versus PGD in COAD, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNB1→partner) and Y-score (partner→GNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PGD →	+0.445	+0.510	<.001	<.001	3	5
OV	ICMT →	+0.491	+0.434	.001	.001	3	5
OV	PANK4 →	+0.299	+0.428	<.001	<.001	3	5
OV	UBE4B →	+0.343	+0.619	<.001	<.001	3	4
UCEC	UBR4 →	+0.180	+0.368	<.001	.009	2	5
PDAC	ARHGEF16 →	+0.541	+0.375	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,736 associations by consensus.

GNB1 vs PGD — COAD

Explore this scatter interactively →