Across TCGA cell cohorts, GNAT3 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GNAT3-associated genes across cancer lineages are LBHD2, OR2V1, and C1orf68. Each is linked with GNAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNAT3-to-partner and partner-to-GNAT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAT3→partner) and Y-score (partner→GNAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LBHD2 →	+0.146	+4.273	<.001	.006	3	2
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
LARGE_INTESTINE	C1orf68 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR4A47 →	+0.022	+5.022	<.001	.002	3	1
LARGE_INTESTINE	LCE1F →	+0.106	+4.415	<.001	.007	3	1
SKIN	GJA10 →	+0.017	+3.930	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

GNAT3 survival (RNA) · tumor vs normal (RNA) · all GNAT3 data types