GNAT1

Across TCGA patient cohorts, GNAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 115 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAT1-associated genes across cancer lineages are GRB10, FGFR1OP2, and HAO2. Each is linked with GNAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNAT1-to-partner and partner-to-GNAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAT1 versus GRB10 in GBM, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAT1→partner) and Y-score (partner→GNAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GRB10 →	+2.299	+1.286	.002	.002	3	1
GBM	FGFR1OP2 →	-0.733	-1.630	.003	.006	3	1
GBM	HAO2 →	-0.579	-1.188	.007	.009	3	1
GBM	NAPSB →	-2.550	-1.629	.003	.006	3	1
GBM	TMEM165 →	-0.391	-1.188	<.001	.009	3	1
GBM	C4orf33 →	-0.983	-1.630	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

GNAT1 vs GRB10 — GBM

Explore this scatter interactively →