GNAT1

Across TCGA cell cohorts, GNAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 485 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible GNAT1-associated GO terms across cancer lineages are G protein-coupled opsin signaling pathway, Negative regulation of mRNA metabolic process, and Late viral transcription. Each is linked with GNAT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GNAT1-to-partner and partner-to-GNAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, G protein-coupled opsin signaling pathway grouped by GNAT1-low versus GNAT1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAT1→partner) and Y-score (partner→GNAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	G protein-coupled opsin signaling pathway →	+0.203	+0.096	.004	.008	3	8
OVARY	Negative regulation of mRNA metabolic process →	+0.074	+0.184	<.001	.006	3	4
BONE	Late viral transcription →	+0.125	+0.036	.001	.009	3	4
BONE	Negative regulation of RNA splicing →	+0.070	+0.030	.005	.007	3	4
SOFT_TISSUE	Schwann cell development →	+0.066	+0.048	.002	.004	3	4
SOFT_TISSUE	Regulation of G0 to G1 transition →	+0.051	+0.045	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 485 associations by consensus.

G protein-coupled opsin signaling pathway by GNAT1 expression — CNS

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