GNAO1

Across TCGA patient cohorts, GNAO1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,681 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAO1-associated genes across cancer lineages are RIC3, ELN, and CPED1. Each is linked with GNAO1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GNAO1-to-partner and partner-to-GNAO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAO1 versus RIC3 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAO1→partner) and Y-score (partner→GNAO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RIC3 →	+1.349	+1.046	<.001	<.001	3	8
OV	ELN →	+1.525	+0.597	<.001	.008	3	8
COAD	CPED1 →	+0.855	+0.759	<.001	<.001	3	7
CCRCC	MFAP4 →	+1.555	+0.447	<.001	<.001	3	7
HNSC	DMD →	+1.160	+0.446	<.001	<.001	3	7
HNSC	RASGRP2 →	+0.757	+0.530	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,681 associations by consensus.

GNAO1 vs RIC3 — OV

Explore this scatter interactively →