GNAL

Across TCGA patient cohorts, GNAL RNA expression is significantly associated with the protein abundance of many other proteins, with 16,638 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GNAL-associated proteins across cancer lineages are CSRP1, EFEMP1, and AKAP12. Each is linked with GNAL in more than 5 cancer types. Because this analysis shows association rather than direction, both GNAL-to-partner and partner-to-GNAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAL versus CSRP1 in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAL→partner) and Y-score (partner→GNAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSRP1 →	+0.985	+0.406	<.001	.001	3	6
UCEC	EFEMP1 →	+1.126	+0.654	<.001	<.001	3	6
UCEC	AKAP12 →	+0.863	+0.541	<.001	<.001	3	6
UCEC	AKAP12_T1116 →	+1.060	+0.591	<.001	.001	3	6
COAD	AKT3 →	+0.828	+0.687	.005	.004	3	6
UCEC	UCHL1 →	+1.046	+0.412	.002	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,638 associations by consensus.

GNAL vs CSRP1 — COAD

Explore this scatter interactively →