GNAI3

Across TCGA patient cohorts, GNAI3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,457 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GNAI3-associated proteins across cancer lineages are NRDC, MOV10, and CTTNBP2NL. Each is linked with GNAI3 in more than 5 cancer types. Because this analysis shows association rather than direction, both GNAI3-to-partner and partner-to-GNAI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAI3 versus NRDC in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAI3→partner) and Y-score (partner→GNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NRDC →	+0.339	+0.487	<.001	<.001	3	6
UCEC	MOV10 →	+0.307	+0.349	.001	<.001	3	5
BRCA	CTTNBP2NL →	+0.285	+0.438	<.001	<.001	3	5
LSCC	MZB1 →	-0.782	-0.424	<.001	.002	3	4
UCEC	NCAPG →	+0.392	+0.256	.002	<.001	3	4
LUAD	NDC80 →	+0.558	+0.289	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,457 associations by consensus.

GNAI3 vs NRDC — HNSC

Explore this scatter interactively →